Aminobenzoic acids and derivatives
Selleck Chemical LLC Cyclosporin A S2286-10mM/1mL
Cyclosporin A a non-polar cyclic oligopeptide is an immunosuppressive agent that binds to cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay Cyclosporin A is generally given following transplant surgery to prevent rejection and has been used to test its toxic effect on a perfused 3D proximal tubule model Cyclosporin A (NSC 290193) can be used to induce animal models of Chronic Rejection of Liver Transplantation
Medchemexpress LLC Luisol A | 225110-59-8 | 99.9% | 1 MG
Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A is an anthraquinone antibiotic analog.
- For research use only.
Chemscene p-Dimethylaminobenzaldehyde | 25g | CS-W020083 | 98% | 100-10-7 | MFCD00003381 | 149 19 | C9H11NO
Chemscene | p-Dimethylaminobenzaldehyde | 25g | CS-W020083 | 98% | 100-10-7 | MFCD00003381 | 149 19 | C9H11NO
Chemscene 5-Bromo-2-methyl-1H-pyrrolo[2 3-b]pyridine | 5g | CS-W008884 | 98% | 1111638-02-8 | MFCD15529124 | 211 062 | C8H7BrN2
Chemscene | 5-Bromo-2-methyl-1H-pyrrolo[2 3-b]pyridine | 5g | CS-W008884 | 98% | 1111638-02-8 | MFCD15529124 | 211 062 | C8H7BrN2
Medchemexpress LLC A-935142 | 1031335-85-9 | 98.8% | 352.35 | 1 MG
A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. It enhances hERG current by facilitating activation, reducing inactivation, and slowing deactivation, which abbreviates atrial and ventricular repolarization.
- For research use only.
- Shortens the action potential duration (APD90) in guinea pig atrial tissue and canine cardiac Purkinje fibers.
- Shortens cardiac action potentials and enhances the amplitude of the hERG current in a concentration- and voltage-dependent manner.
- Increases both outward and inward K(+) current as well as the slope conductance of the linear portion of the fully activated I-V relation (60μM).
- Significantly reduces the time constants τ of hERG channel activation and shifts the voltage-dependence for hERG activation in the hyperpolarizing direction by 9 mV.
Medchemexpress LLC 2-Amino-2-methyl-1-propanol | 124-68-5 | 100.0% | 89.14 | 1 ML
2-Amino-2-methyl-1-propanol (AMP) acts as a neutralizer, buffer, and surfactant. It is known to inhibit gelatinous product formation and is utilized for carbon dioxide absorption.
- Neutralizer, buffer, surfactant: versatile chemical with multiple functions.
- Inhibits gelatinous product formation: prevents the formation of undesirable gelatinous byproducts in non-aqueous CO2 absorbents.
- Carbon dioxide absorption: used in applications requiring CO2 absorption.
- Histochemical applications: can be used for histochemical demonstration of alkaline phosphatase activity (at concentrations of 170-350 mM).
- Safety profile: studies in rats and mice at various doses and exposure routes did not show liver effects or compound-related changes, although some elevated SGPT and OCT serum levels were noted in rats at high oral doses without accompanying gross pathology or histopathology changes.
eMolecules 1679-18-1 | 4-Chlorobenzeneboronic acid | Oakwood Chemicals | MFCD00039137 | 156.370 | C6H6BClO2 | 95.000 | OB(O)c1ccc(Cl)cc1 | 25g | 480110195
4-Chlorobenzeneboronic acid | Oakwood Chemicals | 1679-18-1 | MFCD00039137 | 156.370 | C6H6BClO2 | 95.000 | OB(O)c1ccc(Cl)cc1 | 25g | 480110195
Medchemexpress LLC Cyclohexaneacetic acid | 5292-21-7 | MFCD00001518 | 99.8% | 142.20 g/mol | C8H14O2 | 5 G
Cyclohexaneacetic acid is a research-grade small-molecule carboxylic acid (C8H14O2; 142.20 g/mol) supplied as a solid and used as a chemical intermediate and endogenous metabolite reference in biochemical and pharmacological research, providing defined solubility and storage characteristics for analytical and synthetic workflows.
- High purity: 99.78% (manufacturer reported).
- Solid, colorless to off-white physical state.
- Soluble in DMSO at 100 mg/mL; sonication may be required.
- Stable when stored as powder at -20°C (up to 3 years) or 4°C (up to 2 years).
- Formulation options documented for in vivo use (e.g., DMSO/PEG300/Tween-80/saline).
Chemscene 4-Propylphenylboronic acid | 5g | CS-W016096 | 98% | 134150-01-9 | MFCD00859261 | 164 013 | C9H13BO2
Chemscene | 4-Propylphenylboronic acid | 5g | CS-W016096 | 98% | 134150-01-9 | MFCD00859261 | 164 013 | C9H13BO2
Chemscene (R)-(6 6 -Dimethoxy-[1 1 -biphenyl]-2 2 -diyl)bis(diphenylphosphine) | 1g | CS-W013802 | 98% | 133545-16-1 | MFCD03095430 | 582 62 | C38H32O2P2
Chemscene | (R)-(6 6 -Dimethoxy-[1 1 -biphenyl]-2 2 -diyl)bis(diphenylphosphine) | 1g | CS-W013802 | 98% | 133545-16-1 | MFCD03095430 | 582 62 | C38H32O2P2
Chemscene 5-Methoxypyridin-3-ol | 5g | CS-W011176 | 96% | 109345-94-0 | MFCD06797672 | 125 13 | C6H7NO2
Chemscene | 5-Methoxypyridin-3-ol | 5g | CS-W011176 | 96% | 109345-94-0 | MFCD06797672 | 125 13 | C6H7NO2
Chemscene (2 6-Difluoro-3-nitrophenyl)boronic acid | 10g | CS-W015485 | 98% | 1150114-28-5 | MFCD12025957 | 202 91 | C6H4BF2NO4
Chemscene | (2 6-Difluoro-3-nitrophenyl)boronic acid | 10g | CS-W015485 | 98% | 1150114-28-5 | MFCD12025957 | 202 91 | C6H4BF2NO4
Chemscene 5-Amino-3-bromo-2-chloropyridine | 100g | CS-W020112 | 98% | 130284-53-6 | MFCD03840433 | 207 46 | C5H4BrClN2
Chemscene | 5-Amino-3-bromo-2-chloropyridine | 100g | CS-W020112 | 98% | 130284-53-6 | MFCD03840433 | 207 46 | C5H4BrClN2
TARGETMOL CHEMICALS INC FLOSEQUINAN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Flosequinan is an arteriovenous vasodilator which can effectively treat acute heart failure. purity: 98%
Chemscene 2-(Benzylamino)ethanol | 1kg | CS-W018111 | 98% | 104-63-2 | MFCD00002840 | 151 21 | C9H13NO
Chemscene | 2-(Benzylamino)ethanol | 1kg | CS-W018111 | 98% | 104-63-2 | MFCD00002840 | 151 21 | C9H13NO